REGIONAL CEREBRAL PERFUSION IMAGING IN THE ELDERLY

Abstract
Tomographic emission scintigraphy of the brain using a stationary gamma-camera and rotating slant hole collimator, following intravenous injection of 123I-n-isopropyl p-iodoamphetamine, yields high quality images of regional cerebral blood flow. The technique has been used on 20 geriatric patients and is non-invasive, well-tolerated, and hitherto only associated with trivial adverse effects. It appears to be particularly useful in supporting a clinical diagnosis of multiinfarct disease but the demonstration of zones of underperfused but not necessarily infarcted cerebral tissue may well have wider research implications.

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