Evaluation of the systemic toxicity and pharmacokinetics of the immunoconjugate anti-B4-blocked ricin in non-human primates. Delivered by multiple bolus injections and by continuous infusion
- 31 August 1993
- journal article
- Published by Elsevier in International Journal of Immunopharmacology
- Vol. 15 (6) , 723-736
- https://doi.org/10.1016/0192-0561(93)90145-o
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusionBlood, 1992
- The galactose-binding sites of the cytotoxic lectin ricin can be chemically blocked in high yield with reactive ligands prepared by chemical modification of glycopeptides containing triantennary N-linked oligosaccharidesBiochemistry, 1991
- Redesigning Nature's Poisons to Create Anti-Tumor ReagentsScience, 1987
- The pharmacokinetics and toxicity of murine monoclonal antibodies and of gelonin conjugates of these antibodiesInternational Journal of Immunopharmacology, 1987
- Evidence that pinocytosis in lymphoid cells has a low capacity.The Journal of cell biology, 1986
- In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates. In vivo stability of disulfide-linked immunotoxin conjugates.Journal of Clinical Investigation, 1986
- Study of the plasma clearance of antibody – ricin‐A‐chain immunotoxinsEuropean Journal of Biochemistry, 1986
- Antibody-complement-mediated cytotoxicity is enhanced by ribosome-inactivating proteins.The Journal of Immunology, 1985
- B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes.The Journal of Immunology, 1983
- Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.Journal of Histochemistry & Cytochemistry, 1981