Amyotrophic Lateral Sclerosis: Effect of Serum on Anterior Horn Cells in Tissue Culture

9 February 1973

journal article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 179 (4073) , 579-580
https://doi.org/10.1126/science.179.4073.579

Abstract

A high proportion of diluted serums of patients with amyotrophic lateral sclerosis were toxic to the anterior horn cells of the mouse in tissue culture. This is not a general cytotoxicity, since apparently only the neurons were killed. Serums from other degenerative neurological diseases were inactive.

Keywords

LATERAL SCLEROSIS
HORN
ANTERIOR
DEGENERATIVE NEUROLOGICAL
GENERAL CYTOTOXICITY
DILUTED SERUMS
HIGH PROPORTION
NEUROLOGICAL DISEASES

This publication has 2 references indexed in Scilit:

Toxicity of motor neurone disease serum for myelin in tissue culture.
BMJ, 1965
TISSUE CULTURE STUDIES OF DEMYELINATION^*
Annals of the New York Academy of Sciences, 1965