Exogeneous cyclic AMP blocks the muscarinic receptor-mediated intracellular Ca2+-release in the gastrulating chick embryo cells
- 1 October 1987
- journal article
- Published by Springer Nature in Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen
- Vol. 196 (7) , 464-466
- https://doi.org/10.1007/bf00399147
Abstract
Exogeneous cyclic AMP (cAMP, 10−8M), when added together with acetylcholine (ACh, 500 μM) to dissociated chick embryo cells, blocked the ACh-stimulated increase in the level of cytosolic free Ca2+ ([Ca2+]i). This inhibiting action of exogeneous cAMP is probably mediated by intracellular cyclic GMP (cGMP) and cAMP.Keywords
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