Hypochloremic Metabolic Alkalosis Following Tolazoline-Induced Gastric Hypersecretion
- 1 February 1980
- journal article
- case report
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 65 (2) , 298-300
- https://doi.org/10.1542/peds.65.2.298
Abstract
Gastric hypersecretion following administration of tolazoline resulted in severe hypochloremic alkalosis in an infant with persistent fetal circulation. An initial bolus injection of 2 mg/kg was followed by an infusion of 5 mg/kg/hr for 24 hours. The infusion was then maintained at 2 mg/kg/hr for the next four days. Volume of gastric secretions exceeded 25 ml/kg/24 hr. Weaning from tolazoline and replacement of chloride and potassium corrected the metabolic alkalosis.Keywords
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