Genetic Linkage of Blood Types in the Rabbit

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Abstract
The first clear evidence of linkage between a serological gene and a gene for a morph. character is presented. The A character (presence of the A antigen An vs. the a agglutinin, an) was tested on rabbits over 3 mos. old by both agglutination and inhibition tests. Coupling matings showed no evidence of linkage of an with satin or Vienna white. With Brachydactyl (br), an showed a linkage in both coupling and repulsion matings. The total linkage was statistically significant and showed a crossing over in 36.84 [plus or minus] 3.16. As a 3d gene, furless (f), has been shown to be linked to br with a crossover rate of 28.3, it is probable that the order of the 3 genes is br-f-an. A progress report of the serological H6 antigen shows linkage not to exist with non-agouti, albino, non-extension (yellow), dilute (blue), rex No. 2 short hair, English spotting, Vienna white, br. and rex No. 3.

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