Short and Efficient Large Scale Synthesis of (R)-2-Benzylsuccinic Acid 4-[4-(BOC-amino)-1-piperidide] Monoamide: N-Terminal Component of Renin Inhibitors by Asymmetric Hydrogenation
- 1 January 1993
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1993 (02) , 155-157
- https://doi.org/10.1055/s-1993-22387
Abstract
An economical asymmetric four step synthesis of a 2(R)-benzylsuccinic acid-4-monoamide for use as an N-terminal component in renin inhibitors has been developed (Scheme 3).Keywords
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