Send This Patient's Tumor for Culture and Sensitivity
- 20 January 1983
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 308 (3) , 154-155
- https://doi.org/10.1056/nejm198301203080310
Abstract
One of the primary goals in caring for patients with malignant disease is to provide a treatment program that maximizes the chance of survival and minimizes the side effects of therapy. This goal is particularly important in chemotherapy for cancer.In 1978, Salmon and colleagues1 reported a new in vitro test for determining the sensitivity or resistance of an individual patient's tumor to an anticancer drug. To perform the test, now called the human tumor stem-cell assay, tumor is removed from the patient, made into a suspension of single cells, exposed to the anticancer drug in vitro, and then cultured . . .Keywords
This publication has 9 references indexed in Scilit:
- A Critical Appraisal of the Human Tumor Stem-Cell AssayNew England Journal of Medicine, 1983
- Human colorectal carcinoma: Patterns of sensitivity to chemotherapeutic agents in the human tumor stem cell assayJournal of Surgical Oncology, 1982
- Clinical Correlations With Drug Sensitivities in the Clonogenic AssayArchives of Surgery, 1982
- Quantitation of drug sensitivity by human metastatic melanoma colony-forming unitsBritish Journal of Cancer, 1981
- Use of in Vitro Tests in Predlctlve Cancer ChemotherapyJNCI Journal of the National Cancer Institute, 1981
- Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapyThe American Journal of Medicine, 1981
- An in Vitro Clonal Assay for Bladder Cancer: Clinical Correlation with the Status of the Urothelium in 33 PatientsJournal of Urology, 1980
- Growth of human tumour cell colonies from biopsies using two soft-agar techniquesBritish Journal of Cancer, 1978
- Quantitation of Differential Sensitivity of Human-Tumor Stem Cells to Anticancer DrugsNew England Journal of Medicine, 1978