CIRCULATING ANTICOAGULANT IN CREST SYNDROME
- 1 February 1984
- journal article
- case report
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 23 (1) , 20-23
- https://doi.org/10.1093/rheumatology/23.1.20
Abstract
We report the discovery of a circulating anticoagulant in a patient suffering from CREST syndrome. The patient was first seen with a microangiopathic haemolytic anaemia which led to the diagnosis of the CREST syndrome. Several months later, prior to a cataract operation, a routine coagulation screen (prothrombin time and partial thromboplastin time) was abnormal. Investigation showed the presence of a circulating anticoagulant as well as a decrease in several clotting factors, principally factor VIII C.Keywords
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