Neuronal polarity: from extracellular signals to intracellular mechanisms
Top Cited Papers
- 1 March 2007
- journal article
- review article
- Published by Springer Nature in Nature Reviews Neuroscience
- Vol. 8 (3) , 194-205
- https://doi.org/10.1038/nrn2056
Abstract
After they are born and differentiate, neurons break their previous symmetry, dramatically change their shape, and establish two structurally and functionally distinct compartments - axons and dendrites - within one cell. How do neurons develop their morphologically and molecularly distinct compartments? Recent studies have implicated several signalling pathways evoked by extracellular signals as having essential roles in a number of aspects of neuronal polarization.Keywords
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