Some pharmacological properties of morphine-7,8-oxide (morphine epoxide)
- 1 January 1982
- journal article
- research article
- Published by Pharmaceutical Society of Japan in Journal of Pharmacobio-Dynamics
- Vol. 5 (7) , 505-508
- https://doi.org/10.1248/bpb1978.5.505
Abstract
Morphine-7,8-oxide (morphine epoxide) is a metabolite of morphine. Morphine epoxide in antinociceptive action was practically as potent as morphine. The development of tolerance in antinociceptive action was slower in rats treated with morphine epoxide than in rats treated with morphine. Morphine epoxide was less potent than morphine in the inhibition of abstinence syndrome.This publication has 0 references indexed in Scilit: