25‐Hydroxyvitamin D3 3‐sulphate is a major circulating form of vitamin D in man
- 28 October 1985
- journal article
- Published by Wiley in FEBS Letters
- Vol. 191 (2) , 171-175
- https://doi.org/10.1016/0014-5793(85)80002-8
Abstract
25-Hydroxyvitamin D3 3β-sulphate has been identified in human plasma. The compound was isolated by anion-exchange chromatography and following hydrolysis it was characterized by high-performance liquid chromatography and gas chromatography-mass spectrometry. The mean concentration of sulphated 25-hydroxy vitamin D3 in plasma from 60 patients was 16.7 ±7.1 ngml and the levels often exceeded those of the corresponding free compound. The study also shows that unconjugated 25-hydroxvitamin D3 is not readily sulphated by man in vivoKeywords
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