‘In silico’ simulations to assess the ‘in vivo’ consequences of ‘in vitro’ metabolic drug–drug interactions

This publication has 14 references indexed in Scilit:

• ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
  Drug Metabolism and Disposition, 2004
• Qualitative and Quantitative Assessment of Drug-Drug Interaction Potential in Man, Based on Ki, IC50 and Inhibitor Concentration
  Current Drug Metabolism, 2004
• Database analyses for the prediction of in vivo drug–drug interactions from in vitro data
  British Journal of Clinical Pharmacology, 2004
• The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties
  Drug Metabolism and Disposition, 2002
• Use of in vitro drug metabolism data to evaluate metabolic drug-drug interactions in man: the need for quantitative databases.
  The Journal of Clinical Pharmacology, 2001
• Utility of metabolic stability screening: comparison ofin vitroandin vivoclearance
  Xenobiotica, 2001
• Sense and Nonsense in the Prediction of Drug-Drug Interactions
  Current Drug Metabolism, 2000
• QUANTITATIVE PREDICTION OF IN VIVO DRUG CLEARANCE AND DRUG INTERACTIONS FROM IN VITRO DATA ON METABOLISM, TOGETHER WITH BINDING AND TRANSPORT
  Annual Review of Pharmacology and Toxicology, 1998
• The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes.
  British Journal of Clinical Pharmacology, 1992
• Kinetics of drug-drug interactions
  Journal of Pharmacokinetics and Biopharmaceutics, 1973