Procaine Action: Antagonism by Adenosine Triphosphate and Other Nucleotides
- 5 June 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3623) , 1222-1223
- https://doi.org/10.1126/science.144.3623.1222
Abstract
Appropriate concentrations of adenosine tri-, di-, and monophosphate antagonize the depressant action of procaine on isolated nerve. Some calcium ion is required in the external solution in order for these nucleotides to produce their maximum effects. When applied either to normal or sodium deficient nerves, the nucleotides do not increase action-potential amplitude.Keywords
This publication has 3 references indexed in Scilit:
- Effect of Azide and Ca Ion on the Reversible Changes of Protein Configuration in Stimulated NervesThe Journal of general physiology, 1963
- Phospholipid-Cholesterol Membrane ModelThe Journal of general physiology, 1962
- Outflux of various phosphates during membrane depolarization of excitable tissuesAmerican Journal of Physiology-Legacy Content, 1962