Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis
Open Access
- 1 April 2005
- journal article
- review article
- Published by Oxford University Press (OUP) in Neuro-Oncology
- Vol. 7 (2) , 134-153
- https://doi.org/10.1215/s1152851704001115
Abstract
Glioblastomas, like other solid tumors, have extensive areas of hypoxia and necrosis. The importance of hypoxia in driving tumor growth is receivingKeywords
This publication has 101 references indexed in Scilit:
- Expression and Characterization of Hypoxia-Inducible Factor (HIF)-3α in Human Kidney: Suppression of HIF-Mediated Gene Expression by HIF-3αBiochemical and Biophysical Research Communications, 2001
- Erythropoietin stimulates proliferation of human renal carcinoma cellsKidney International, 2000
- Characterization and Expression of a Novel Alternatively Spliced Human Angiopoietin-2Published by Elsevier ,2000
- Identification of Alternative Spliced Variants of Human Hypoxia-inducible Factor-1αPublished by Elsevier ,2000
- Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3Journal of Clinical Investigation, 2000
- Hypoxia Regulates Expression of the Endothelin-1 Gene through a Proximal Hypoxia-Inducible Factor-1 Binding Site on the Antisense StrandBiochemical and Biophysical Research Communications, 1998
- Enhanced expression of transforming growth factor‐β and its type‐I and type‐II receptors in human glioblastomaInternational Journal of Cancer, 1995
- Effect of endothelin-1 as growth factor on a human glioma cell line; its characteristic promotion of DNA synthesisJournal of Neuro-Oncology, 1994
- TM-1 cells from an established human malignant glioma cell line produce PDGF, TGF-?, and TGF-? which cooperatively play a stimulatory role for an autocrine growth promotionJournal of Neuro-Oncology, 1994
- Cellular sites of extrarenal and renal erythropoietin production in anaemic ratsBritish Journal of Haematology, 1992