Amniotic graft in the management of severe epistaxis due to hereditary haemorrhagic telangiectasia

Abstract
In selected cases [6] of hereditary hemorrhagic telangiectesia with severe, life-threatening epistaxis, a new surgical procedure was performed, consisting of a thorough, near total excision of the diseased nasal mucosa and its replacement by an amniotic membrane graft. The surgical details of the preparation of the amniotic graft are described. During 9-30 mo. of follow-up, no nasal bleeding occurred and the Hb level was normal. The amniotic membrane served as an adequate grafting material for the lining of the nasal chambers.