Absent chondrodysplasia punctata in a male with an Xp terminal deletion involving the putative region for CDPX1 locus

Abstract
This is a follow‐up report on a male patient with a 46, Y, r(X) karyotype. Although he had no clinico‐radiological features of X‐linked recessive chondrodysplasia punctata (CDPX1), molecular studies revealed an Xp terminal deletion involving the putative region for the CDPX1 locus (PABXDXS31). We suspect that the absence of CDPX1 may be attributable to the nature of the disease and the extreme short stature of the patient (mean – 5.6 S.D.).