Chromosomes in acute leukemia
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 53 (1) , 5-16
- https://doi.org/10.1007/bf00289443
Abstract
The karyotype of leukemic cells of 78 acute leukemia patients (37 ANLL, 34ALL, and 7 of unknown type) was studied by means of G-banding. Chromsomal abnormalities were found in 50 patients (72%). Chromosomes 8, 21, 5, 7, 11, and 19 were preferentially involeved in the abnormalities, both in ANLL and in ALL. A high incidence of the characteristic rearrangement t(8,21) was noted in AML: (in 6 of 22 AML patients). An identical reciprocal translocation—t(4;11)—was seen in 4 out of 34 ALL patients.This publication has 23 references indexed in Scilit:
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