Minimization of the number of pregnant women to be treated with preventive procedure against GBS infection by means of antibody measurement
- 1 October 1997
- journal article
- clinical trial
- Published by Wiley in Pediatrics International
- Vol. 39 (5) , 546-549
- https://doi.org/10.1111/j.1442-200x.1997.tb03638.x
Abstract
To study preventive strategies, it is essential to screen pregnant women having group B Streptococcus (GBS) infection in the birth canal. For the purpose of studying preventive measures against this infection, nationwide multicenter research was performed in GBS‐carrying pregnant women. Of a total of 10 267 pregnant women, 1860 cases (18.1%) had GBS. The most common serotypes of detected GBS were type NT6 and JM9, followed by type III, type Ia and then type Ib. Type‐specific antibody titer was below the cut‐off point of 10 units/mL in 30.9% of Ia carriers, 58.5% of Ib carriers, 45.9% of II carriers and 32.9% of III carriers. Fortunately, no neonatal GBS infection occurred during this research. We concluded that 18.1% of studied pregnant women were GBS carriers and one‐third of these GBS carriers required preventive procedures with antibody measurement.Keywords
This publication has 10 references indexed in Scilit:
- Invasive Group B Streptococcal Disease: The Emergence of Serotype VThe Journal of Infectious Diseases, 1996
- Quantitative Determination of Antibodies to Type III Group B Streptococcal PolysaccharideThe Journal of Infectious Diseases, 1996
- Early-onset group B streptococcal sepsis: A current assessmentThe Journal of Pediatrics, 1992
- Immunization of Pregnant Women with a Polysaccharide Vaccine of Group B StreptococcusNew England Journal of Medicine, 1988
- Functional Activity of Class-Specific Antibodies to Type III, Group B StreptococcusPediatric Research, 1988
- Epidemiology of Group B Streptococcus: Longitudinal Observations during PregnancyThe Journal of Infectious Diseases, 1978
- Quantitative determination of antibody to capsular polysaccharide in infection with type III strains of group B Streptococcus.Journal of Clinical Investigation, 1977
- The Emergence of Group B Streptococci in Infections of the Newborn InfantAnnual Review of Medicine, 1977
- Antibiotic treatment of parturient women colonized with group B streptococciAmerican Journal of Obstetrics and Gynecology, 1976
- Transmission of group B streptococci among parturient women and their neonatesThe Journal of Pediatrics, 1973