Phosphatidylinositol 3-Kinase Signaling Is Important for Smooth Muscle Cell Replication After Arterial Injury
- 1 November 2000
- journal article
- other
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 20 (11) , 2373-2378
- https://doi.org/10.1161/01.atv.20.11.2373
Abstract
—The phosphoinositide 3-kinase [PI(3)K] pathway is a key signaling pathway important for replication of mammalian cells. In this study, we examined the role of PI(3)K in smooth muscle cell ...Keywords
This publication has 29 references indexed in Scilit:
- How do small GTPase signal transduction pathways regulate cell cycle entry?Current Opinion in Cell Biology, 1999
- Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localizationGenes & Development, 1998
- Further evidence that the inhibition of glycogen synthase kinase‐3β by IGF‐1 is mediated by PDK1/PKB‐induced phosphorylation of Ser‐9 and not by dephosphorylation of Tyr‐216FEBS Letters, 1997
- Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death MachineryCell, 1997
- Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 TranslocationJournal of Biological Chemistry, 1996
- Phosphoinositide kinasesCurrent Opinion in Cell Biology, 1996
- Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase BNature, 1995
- Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinaseTrends in Biochemical Sciences, 1995
- Platelet-derived growth factor stimulates synthesis of Ptdlns(3,4,5)P3 by activating a Ptdlns(4,5)P2 3-OH kinaseNature, 1992
- PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cellsCell, 1989