Abstract
Dyskinesia developed in 4 patients soon after the administration of therapeutic doses of dextroamphetamine sulfate. The movements were tic-like, dystonic, and similar to those occasionally produced by pheno-thiazines, and they promptly disappeared when the use of the drug ceased. They probably represented idiosyncratic reactions rather than extension of the pharmacologic effects of amphetamines. It is possible that the dextroamphetamine unmasked a subclinical extrapyramidal disorder in these patients.

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