A repeat sequence, GGGTTA, is shared by DNA of human herpesvirus 6 and Marek's disease virus
Open Access
- 1 December 1988
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 62 (12) , 4824-4827
- https://doi.org/10.1128/jvi.62.12.4824-4827.1988
Abstract
Some regions of the genomes of human B-lymphotrophic virus (HBLV), also designated as human herpesvirus 6, and Marek9s disease virus were found to hybridize to each other under moderate to stringent conditions, scoring from 10 to 30% base-pair mismatch. Nucleotide sequence analysis showed that a 6-base-pair repetitive sequence, GGGTTA (DR2), present in the IRS-IRL junction region of the Marek9s disease virus genome, was also reiterated in the HBLV genome. The function(s) of such a sequence is unknown, but this is the first report of homology between HBLV and a nonhuman herpesvirus. ImagesThis publication has 32 references indexed in Scilit:
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