Effect of Pentagastrin and Gastric Alkalinization on Lower Esophageal Sphincter Pressure in Diffuse Esophageal Spasm
- 1 January 1975
- journal article
- research article
- Published by S. Karger AG in Digestion
- Vol. 13 (1-2) , 1-7
- https://doi.org/10.1159/000197689
Abstract
The purpose of this study was to evaluate the effect of intravenous pentagastrin and gastric alkalinization on the lower esophageal sphincter (LES) pressure in seven patients with diffuse esophageal spasm as compared to nine normal controls. Intravenous injections of 0.2 and 0.4 μg pentagastrin/kg body weight increased LES pressure significantly more in patients than in control subjects (pKeywords
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