An alternative function for human uncoupling protein 3: protection of mitochondria against accumulation of nonesterified fatty acids inside the mitochondrial matrix
Open Access
- 1 November 2001
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 15 (13) , 2497-2502
- https://doi.org/10.1096/fj.01-0400hyp
Abstract
The physiological function of the human uncoupling protein 3 UCP3, which was discovered in 1997, is unknown. Here we evaluate the available data on human UCP3 expression and show that UCP3 is up-regu...Keywords
This publication has 43 references indexed in Scilit:
- The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCPBiochemical Journal, 2000
- Structure–Function Relationship in UCP1International Journal of Obesity, 1999
- Human Uncoupling Proteins and ObesityObesity Research, 1999
- The uncoupling proteins, a reviewActa Endocrinologica, 1998
- Fatty acid cycling mechanism and mitochondrial uncoupling proteinsBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1998
- Uncoupling Protein-3 Expression in Rodent Skeletal Muscle Is Modulated by Food Intake but Not by Changes in Environmental TemperatureJournal of Biological Chemistry, 1998
- Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and LeptinJournal of Biological Chemistry, 1997
- Uncoupling protein‐3: a new member of the mitochondrial carrier family with tissue‐specific expressionFEBS Letters, 1997
- Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human ThermogenesisDiabetes, 1997
- Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemiaNature Genetics, 1997