Long-term heavy amphetamine use can cause a variety of health and social problems, yet few amphetamine users seek professional help. When they do overcome the barriers and present to a drug agency, many never return after the initial visit. This paper focuses on amphetamine users who presented to treatment services in the North-West of England, but who failed to re-attend. The profile of those who left treatment describes amphetamineusers who are likely to be younger, on probation, using more recreational drugs and whose parents are aware of their attendance at a drug service. Analyses of the changes in amphetamine use over time show an initial decline in the frequency and amount of amphetamine used for the 'early leavers', similar to that of amphetamine users who are continuing in treatment. This reduction is not replicated by the early leavers in the second month, although it becomes more pronounced for those still receiving treatment. It is suggested that the high degree of motivation required by amphetamine users to seek help from a drug service provides a strong incentive for preliminary behaviour change even without continued treatment. However, sustained reduction in amphetamine use is assisted by the support and guidance of skilled drug workers.