Alpha-thalassemia in blacks: genetic and clinical aspects and interactions with the sickle hemoglobin gene.

  • 1 November 1986
    • journal article
    • review article
    • Vol. 68  (5) , 985-90
Abstract
Recent advances in molecular genetics have permitted detailed study of the human alpha-globin genes and the causes of alpha-thalassemia. In this review, we examine the causes of alpha-thalassemia in the black population and the consequences of the interactions between alpha-thalassemia and structural hemoglobin variants.

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