Somatosensory Evoked Potentials and Cognitive Sequelae in Children with Closed Head-Injury

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Abstract
In search of a prognostic indicator for residual cognitive function loss in children after closed head-injury, the somatosensory evoked potential P300 has been studied in a prospective follow-up study of 17 patients with mild and moderately severe head-injuries. The P300 response was measured in the acute phase after patients regained consciousness. In addition the duration of coma and of post-traumatic amnesia were recorded. An age-matched control group of 20 healthy children supplied age-related normative evoked potential data. During a two-years follow-up period the presence of residual disorders in various faculties was evaluated at fixed time intervals after discharge. Correlation analyses revealed that, where the duration of coma and of post-traumatic amnesia qualify as general predictors of sequelae, the long-latency somatosensory evoked potential P300 correlated specifically with long-term deficits in the field of school performance.

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