Configurational and conformational studies of N,N‐dimethylpiperidinium derivatives by 13C and 1H NMR spectroscopy
- 1 March 1982
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Chemistry
- Vol. 18 (3) , 171-175
- https://doi.org/10.1002/mrc.1270180312
Abstract
The 13C and 1H NMR spectra of a series of methiodides of mono‐ and di‐C‐methyl derivatives of 1‐methyl‐4‐phenyl‐4‐piperidinols are reported and chemical shift data analysed in terms of configurations and conformations of isomeric sets. Results demondtrate the value of quaternary salt NMR data as an aid to configurational assignment, and the evaluation of non‐bonded interactions governing conformational equilibria in piperidine derivatives.Keywords
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