THE NONMUTAGENIC ACTION OF p-p′-DDT AND γ-HEXACHLOROCYCLOHEXANE IN DROSOPHILA MELANOGASTER MEIG. (DIPTERA: DROSOPHILIDAE)

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Abstract
As experiments are in progress on selective breeding for insecticide tolerance in insect parasites and as various physiologically potent chemicals have been shown to cause mutation in Drosophila melanogaster Meig., tests were made to determine whether p-p′-DDT and γ-hexachlorocyclohexane had any mutagenic action. Wild type males of D. melanogaster that had been exposed to the former insecticide in their larval feeding medium, or, as adults, to the vapor of the latter insecticide, were tested. The Muller-5 method of detecting recessive lethal mutations in the X chromosome was used. No evidence of mutagenic action was found in either insecticidal isomer.

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