The Role of Systemic Chemotherapy in the Treatment of Kidney Cancer

Abstract
The prognosis for patients with metastatic renal cell carcinoma (RCC) is poor. The median overall survival time of patients with advanced disease is approximately 10 months with a 3-year survival rate of about 10%1. RCC is typically described as chemotherapy (and radiation therapy) resistant. Most authors agree that biologic response modifiers (i e immunotherapy) represent standard first-line treatment for advanced RCC.