Characterization of a Putative Retroviral Env-Related Human Protein
- 1 January 1997
- journal article
- Published by S. Karger AG in Pathobiology
- Vol. 65 (3) , 123-128
- https://doi.org/10.1159/000164113
Abstract
In this study, we developed a rabbit polyclonal antibody to a fusion protein containing the envelope (env) transmembrane (TM) region from the human endogenous retroviral family, HERV-E. We used this reagent to document the expression of TM-related protein by Western blot in endothelial, colon and prostate carcinoma and seminoma cell lines and in peripheral blood mononuclear cells from a healthy donor. We detected a 58-kD protein (as compared to murine TM of 15 kD) that had specificity for the env-related antibodies of the polyclonal antiserum.Keywords
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