Scalable, efficient process for the synthesis of (R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion complex

This publication has 14 references indexed in Scilit:

• Efficient Synthesis of NK₁ Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation
  Journal of the American Chemical Society, 2003
• Practical Asymmetric Synthesis of Aprepitant, a Potent Human NK-1 Receptor Antagonist, via a Stereoselective Lewis Acid-Catalyzed Trans Acetalization Reaction
  The Journal of Organic Chemistry, 2002
• Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
  Angewandte Chemie International Edition in English, 2001
• Practical Synthesis of (S)-1-(3-Trifluoromethylphenyl)ethanol via Ruthenium(II)-catalyzed Asymmetric Transfer Hydrogenation
  Organic Process Research & Development, 2000
• Asymmetric transfer hydrogenation of CO and CN bonds
  Tetrahedron: Asymmetry, 1999
• New Chiral Rhodium and Iridium Complexes with Chiral Diamine Ligands for Asymmetric Transfer Hydrogenation of Aromatic Ketones
  The Journal of Organic Chemistry, 1999
• Asymmetric Transfer Hydrogenation Catalyzed by Chiral Ruthenium Complexes
  Accounts of Chemical Research, 1997
• Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using a Formic Acid−Triethylamine Mixture
  Journal of the American Chemical Society, 1996
• Asymmetric Transfer Hydrogenation of Aromatic Ketones Catalyzed by Chiral Ruthenium(II) Complexes
  Journal of the American Chemical Society, 1995
• A practical process for the preparation of tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole-borane. A highly enantioselective stoichiometric and catalytic reducing agent
  The Journal of Organic Chemistry, 1993