Monitoring multi‐armed trials

15 July 1994

journal article
research article
Published by Wiley in Statistics in Medicine

Vol. 13 (13-14) , 1441-1452
https://doi.org/10.1002/sim.4780131320

Abstract

We propose and discuss several methods of monitoring multi-armed trials comparing means or survival. These methods combine multiple comparison procedures such as Fisher's LSD, Newman-Keuls and Tukey's with monitoring boundaries such as those of O'Brien and Fleming and Lan and DeMets. Tables of boundaries are provided for the equal variance or equal censoring distribution case.

Keywords

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