The ftsA gene product participates in formation of the Escherichia coli septum structure

Publisher Website
Google Scholar
Abstract
The patterns of septation in filaments of E. coli, formed as a consequence of the lack of an active ftsA gene product and then returned to permissive conditions, were analyzed in isogenic strains containing 3 different mutated alleles of ftsA. Septation was blocked for at least 1 doubling time at the potential septation sites that presumably contained inactive FtsA protein but not at those sites containing either the active gene product or no gene product at all. These results suggested a possible structural role for the ftsA gene product in the construction of the E. coli septum.