METABOLIC STUDIES WITH METHANDROSTENOLONE (17β-HYDROXY-17α-METHYL-ANDROSTA-1,4-DIEN-3-ONE) IN HUMAN SUBJECTS
- 1 November 1961
- journal article
- research article
- Published by Bioscientifica in Acta Endocrinologica
- Vol. 38 (3) , 413-418
- https://doi.org/10.1530/acta.0.0380413
Abstract
The effect of graded doses (5, 10 and 25 mg/d of methandrostenolone and of 25 mg/d of testosterone propionate were compared in each of three metabolically stable adult subjects. Five mg/d of methandrostenolone induced nitrogen and calcium retention. The effects observed with larger doses of methandrostenolone (10 and 25 mg/d) were not quantitatively different from those with 5 mg/d. The nitrogen and calcium retention obtained with the daily dose of 5 mg of methandrostenolone was as great or greater than that induced by testosterone propionate (25 mg/d). Methandrostenolone induced creatinuria but had no effect on sodium and chloride balances and urinary excretion of 17-ketosteroids.Keywords
This publication has 1 reference indexed in Scilit:
- THE EFFECT OF HUMAN GROWTH HORMONE IN MANActa Endocrinologica, 1959