Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91phox/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67phox, and p47phox
Open Access
- 21 November 2008
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 23 (4) , 1011-1022
- https://doi.org/10.1096/fj.08-114553
Abstract
Neutrophils generate microbicidal oxidants through activation of a multicomponent enzyme called NADPH oxidase. During activation, the cytosolic NADPH oxidase components (p47phox, p67phox, p40phox, an...Keywords
Funding Information
- Fondation pour la Recherche Médicale
- Australian Research Council
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