STIMULATION AND SENSITIZATION OF THE ISOLATED VENUS HEART BY CEREBROSPINAL FLUID
Open Access
- 1 October 1962
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 19 (2) , 295-298
- https://doi.org/10.1111/j.1476-5381.1962.tb01191.x
Abstract
5-Hydroxytryptamine was not detected in animal cerebrospinal fluid after amine oxidase inhibitors, reserpine, or both. Both human and animal cerebrospinal fluid can produce a stimulating effect on the clam heart which is not due to 5-hydroxytryptamine. Cerebrospinal fluid also has the property of increasing the sensitivity of the clam heart to 5-hydroxytryptamine.Keywords
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