THE EFFECT OF INTRAVENOUS INFUSIONS OF PHYSIOLOGIC SALINE SOLUTION ON THE PULMONARY ARTERIAL AND PULMONARY CAPILLARY PRESSURE IN MAN 1
Open Access
- 1 April 1951
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 30 (4) , 345-352
- https://doi.org/10.1172/jci102450
Abstract
In the normal human subject the pulmonary arterial and the pulmonary capillary pressure can be significantly increased by the rapid intravenous infusion of physiologic saline soln. The pulmonary and the general blood volumes increase proportionately after this maneuver. The cardiac output after a rapid infusion may or may not increase. There is a linear correlation between the resting pulmonary arterial pressure and the general blood volume in normal subjects, but this relationship is not apparent in the case of the pulmonary blood volume as measured by the dye technic. The same relationship continues after an increase in the blood volume with saline soln. It is suggested that the changes induced by a rapid infusion can be explained most adequately on the basis of an abrupt, but not disproportionate, increase in the amt. of blood contained in the relatively indistensible pulmonary circuit.Keywords
This publication has 10 references indexed in Scilit:
- STUDIES OF THE PULMONARY CIRCULATION IN MAN AT REST. NORMAL VARIATIONS AND THE INTERRELATIONS BETWEEN INCREASED PULMONARY BLOOD FLOW, ELEVATED PULMONARY ARTERIAL PRESSURE, AND HIGH PULMONARY “CAPILLARY” PRESSURES 1Journal of Clinical Investigation, 1950
- PULMONARY VASCULAR PRESSURES IN RELATION TO EDEMA PRODUCTION BY AIRWAY RESISTANCE AND PLETHORA IN DOGSAmerican Journal of Physiology-Legacy Content, 1950
- STUDIES OF THE PULMONARY CIRCULATION. I. THE CIRCULATION TIME FROM THE PULMONARY ARTERY TO THE FEMORAL ARTERY AND THE QUANTITY OF BLOOD IN THE LUNGS IN NORMAL INDIVIDUALS 12Journal of Clinical Investigation, 1949
- Pulmonary Capillary Pressure in ManJournal of Applied Physiology, 1949
- Studies on the Circulation of Blood in Man VI. The Pulmonary Capillary Venous Pressure Pulse in ManScandinavian Journal of Clinical and Laboratory Investigation, 1949
- STUDY OF SIMULTANEOUS RIGHT AND LEFT ATRIAL PRESSURE PULSES UNDER NORMAL AND EXPERIMENTALLY ALTERED CONDITIONSAmerican Journal of Physiology-Legacy Content, 1948
- In vivo Observations on the Distensibility of the Femoral Venous System.Experimental Biology and Medicine, 1948
- EFFECT OF EXERCISE ON CARDIAC OUTPUT AND PULMONARY ARTERIAL PRESSURE IN NORMAL PERSONS AND IN PATIENTS WITH CARDIOVASCULAR DISEASE AND PULMONARY EMPHYSEMA 1Journal of Clinical Investigation, 1948
- THE INFLUENCE OF THE COLLAPSIBILITY OF VEINS ON VENOUS PRESSURE, INCLUDING A NEW PROCEDURE FOR MEASURING TISSUE PRESSUREJournal of Clinical Investigation, 1944
- STUDIES ON THE CIRCULATIONAmerican Journal of Physiology-Legacy Content, 1932