12-Month Study of Haloperidol Decanoate in Chronic Schizophrenie Patients
- 1 July 1982
- journal article
- research article
- Published by S. Karger AG in International Pharmacopsychiatry
- Vol. 17 (4) , 247-254
- https://doi.org/10.1159/000468581
Abstract
239 psychotic patients entered a 52-week open study comparing the efficacy and safety of intramuscular haloperidol decanoate, injected once every 4 weeks, with that of their previous maintenance therapy. Haloperidol decanoate, given at a medium monthly dose of 100 mg provided a suitable substitute for oral neuroleptic mono- and polytherapy and intramuscular fluphenazine decanoate. Stabilization or slight improvement was observed for all ten symptoms selected from the BPRS. The drug provoked a low incidence of side-effects allowing reduction of antiparkinsonian medication and there were no significant haematological or biochemical changes.Keywords
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