Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen

This publication has 13 references indexed in Scilit:

• Combined HPLC, NMR Spectroscopy, and Ion-Trap Mass Spectrometry with Application to the Detection and Characterization of Xenobiotic and Endogenous Metabolites in Human Urine
  Analytical Chemistry, 1996
• 1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat
  Biochemical Pharmacology, 1995
• Evaluation of liquid chromatography coupled with high-field1H NMR spectroscopy for drug metabolite detection and characterization: The identification of paracetamol metabolites in urine and bile
  NMR in Biomedicine, 1994
• Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra
  Journal of Pharmaceutical and Biomedical Analysis, 1994
• Deuterium NMR spectroscopy of biofluids for the identification of drug metabolites: Application to N,N-dimethylformamide
  Journal of Pharmaceutical and Biomedical Analysis, 1993
• High-performance liquid chromatography coupled to high-field proton nuclear magnetic resonance spectroscopy: application to the urinary metabolites of ibuprofen
  Analytical Chemistry, 1993
• Acyl Glucuronides Revisited: Is the Glucuronidation Proces a Toxification as Well as a Detoxification Mechanism?
  Drug Metabolism Reviews, 1992
• Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine
  Journal of Pharmaceutical and Biomedical Analysis, 1988
• Solid-phase extraction chromatography and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine
  Analytical Chemistry, 1987
• Irreversible binding of zomepirac to plasma protein in vitro and in vivo.
  Journal of Clinical Investigation, 1986