Proportion of Invasive Pneumococcal Infections in German Children Preventable by Pneumococcal Conjugate Vaccines
- 1 August 2000
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 31 (2) , 482-487
- https://doi.org/10.1086/313984
Abstract
Different age groups were as follows: children aged !1 year, 18.9 (9.7 for meningitis); children aged !2 years, 16.0 (7.2 for meningitis); for children aged !5 years, 8.9 (3.9 for meningitis); and for children aged !16 years, 3.2 (1.4 for meningitis). The proportions of cases involving strains (304 serotyped) included in conjugate vaccines were as follows: for the 7-valent vaccine, 52%; for the 9-valent, 62%; and for the 11-valent, 71%. None of the isolates were resistant to penicillin or cefotaxime. Although the rate for meningitis is similar, other manifestations of IPD are less commonly diagnosed in Germany than in other countries. The serotype distrib- ution only partially matched that used in the recent development of pneumococcal conjugate vaccines.Keywords
This publication has 20 references indexed in Scilit:
- Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in childrenThe Pediatric Infectious Disease Journal, 2000
- Prospective multicentre hospital surveillance of Streptococcus pneumoniae disease in IndiaThe Lancet, 1999
- Safety and Immunogenicity of Heptavalent Pneumococcal Vaccine Conjugated to CRM197 in United States InfantsPediatrics, 1998
- Epidemiology of invasive pneumococcal infections in infants and young children in Metropolitan Santiago, Chile, a newly industrializing countryThe Pediatric Infectious Disease Journal, 1998
- Bacterial Meningitis in the United States in 1995New England Journal of Medicine, 1997
- SEROTYPE DISTRIBUTION AND ANTIBIOTIC SUSCEPTIBILITY OF STREPTOCOCCUS PNEUMONIAE ISOLATES CAUSING SYSTEMIC INFECTIONS AMONG CHILDREN IN GERMANY, 1992 TO 1996The Pediatric Infectious Disease Journal, 1997
- Invasive pneumococcal infection in children, 1981‐92: A hospital‐based studyJournal of Paediatrics and Child Health, 1995
- USE AND LIMITATIONS OF THE CAPTURE-RECAPTURE METHOD IN DISEASE MONITORING WITH TWO DEPENDENT SOURCESEpidemiology, 1995
- Epidemiology of Invasive Childhood Pneumococcal Infections in IsraelPublished by American Medical Association (AMA) ,1992
- Pneumococcal Bacteremia in Charleston County, South CarolinaArchives of internal medicine (1960), 1990