Constitutional Karyotype in Retinoblastoma Case Report and Review of Literature
- 1 January 1989
- journal article
- case report
- Published by Taylor & Francis in Ophthalmic Paediatrics and Genetics
- Vol. 10 (2) , 129-149
- https://doi.org/10.3109/13816818909088353
Abstract
High resolution karyotype was performed in 13 retinoblastoma patients. A mosaic pattern for del(13)(q14.1; q14.3) was found in a girl with sporadic bilateral retinoblastoma and mid-face dysmorphism. In addition, 162 cases of 13q aberrations were reviewed, including 140 retinoblastoma patients and 22 non-penetrance 13q14 deletions. Some epidemiological and genetic involvements are discussed.Keywords
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