American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
Open Access
- 1 October 1987
- journal article
- research article
- Published by FapUNIFESP (SciELO) in Revista do Instituto de Medicina Tropical de São Paulo
- Vol. 29 (5) , 284-288
- https://doi.org/10.1590/s0036-46651987000500004
Abstract
Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure.This publication has 13 references indexed in Scilit:
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