The Regioselective 4-Benzylation of 2,4-Dihydroxybenzaldehyde
- 1 February 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (3) , 593-601
- https://doi.org/10.1080/00397919608003653
Abstract
A regioselective mono-benzylation of the 4-hydroxyl group of 2,4-dihydroxybenzaldehyde (2) to produce 1 under extremely mild basic conditions (NaHCO3 or KF) has been developed. This approach gives improved regioselectivity relative to earlier methods.Keywords
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