EFFECTS OF HEROIN AND METHADONE ON PLASMA CORTISOL AND TESTOSTERONE
- 1 January 1975
- journal article
- research article
- Vol. 195 (2) , 296-302
Abstract
Narcotic addicts self-administered heroin i.v. for 10 days under controlled research ward conditions and were subsequently detoxified with methadone for 7 days. Plasma testosterone levels decreased significantly when heroin dosage was between 45 and 65 mg/day contrasted to predrug base-line levels. Testosterone levels remained depressed during methadone withdrawal. No statistically significant changes in morning plasma cortisol levels were observed during both heroin acquisition and methadone withdrawal.This publication has 8 references indexed in Scilit:
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