Methionine+cystine requiremetns of growing pigs

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Abstract
1. The ovulation rate of forty-eight Scottish half-bred ewes was increased by using pregnant mare's serum gonadotrophin thus inducing litters of one to four foetuses. 2. The effects of increased litter size upon the foetal growth rate and upon the rate of transfer of calcium and phosphorus across the placenta were studied at 108–112, 122–126 and 136–140 d gestation. 3. The number of foetuses had little effect upon foetal weight at 112 d, the mean weights of a singleton, twin, triplet or quadruplet being similar. However, by 140 d mean foetal weight decreased markedly as litter size increased. 4. Failure of individual quadruplets to grow as fast as a singleton was associated with a limitation in the capacity of the placenta for transferring minerals. The maximum rates of transfer of Ca and P, whatever the number of foetuses, were approximately 2·8 and 1·4 g/d respectively. These rates were attained by 112 d when quadruplets were being carried, by 126 d for triplets, and by 140 d for twins.