Combination Intracavitary Chemotherapy for Malignant Pleural Disease
- 1 January 1984
- journal article
- research article
- Published by Mary Ann Liebert Inc in Cancer Drug Delivery
- Vol. 1 (4) , 333-336
- https://doi.org/10.1089/cdd.1984.1.333
Abstract
Seven previously heavily pretreated patients with malignant pleural disease and effusions were treated with 12 courses of combination intrapleural chemotherapy with cisplatin, cytarabine, and doxorubicin. Two patients with ovarian cancer metastatic to the pleura demonstrated dramatic clinical improvement following therapy. Local pain, nephrotoxicity, or bone marrow suppression were not observed during this trial. Further investigation of intrapleural therapy utilizing an escalated dose of cytarabine is warranted.This publication has 4 references indexed in Scilit:
- Intraperitoneal Cisplatin with Systemic Thiosulfate ProtectionAnnals of Internal Medicine, 1982
- Pleural Effusion from MalignancyAnnals of Internal Medicine, 1978
- Carcinomatous involvement of the pleuraThe American Journal of Medicine, 1977