Mercurialism

Abstract
THE many years of clinical experience with mercurial diuretics have established these drugs as effective and relatively nontoxic.Although the literature contains many reports of toxicity from parenteral administration of mercurial medication there are few reports of toxicity resulting from the use of mercurial diuretics given by mouth. Batterman, DeGraff and Shorr1 described early mercurialism in 3 patients using mercurophylline (Mercupurin) § by mouth. This was manifested by gastrointestinal symptoms and increasing albuminuria. One of these patients had severe gingivitis and an elevation of blood nonprotein nitrogen to 52 mg. per 100 cc. A fourth patient showed an elevation of nonprotein . . .