Measurement of Endogenous Carbon Monoxide Formation in Biological Systems
- 1 April 2002
- journal article
- review article
- Published by Mary Ann Liebert Inc in Antioxidants and Redox Signaling
- Vol. 4 (2) , 271-277
- https://doi.org/10.1089/152308602753666325
Abstract
Endogenous carbon monoxide (CO) formation has been measured in different biological systems using a variety of analytical procedures. The methods include gas chromatography-reduction gas detection, gas chromatography-mass spectroscopic detection, laser sensor-infrared absorption, UV-visible spectrophotometric measurement of CO-hemoglobin or CO-myoglobin complex, and formation of 14CO from 14C-heme formed following [2-14C]glycine administration. CO formation ranged from a low of 0.029 nmol/mg of protein/h in chorionic villi of term human placenta to a high of 0.28 nmol/mg of protein/h in rat olfactory receptor neurons in culture and rat liver perfusate.Keywords
This publication has 23 references indexed in Scilit:
- Basic Fibroblast Growth Factor Modulates the Surface Expression of Effector Cell Molecules and Primes Respiratory Burst Activity in Human NeutrophilsActa Haematologica, 2000
- Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental functionThe FASEB Journal, 2000
- Concentration of Carbon Monoxide (CO) in TissuePediatric Research, 1999
- Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy.Journal of Clinical Investigation, 1998
- Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation.Journal of Clinical Investigation, 1998
- Carbon monoxide formation in the guinea pig hippocampus: ontogeny and effect of in vitro ethanol exposureDevelopmental Brain Research, 1997
- THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger GasesAnnual Review of Pharmacology and Toxicology, 1997
- Carbon Monoxide: An Endogenous Modulator of the Nitric Oxide–Cyclic GMP Signaling SystemNeuron, 1996
- Direct demonstration of a physiological role for carbon monoxide in olfactory receptor neuronsJournal of Neuroscience, 1995
- Carbon monoxide does not inhibit glyceryl trinitrate biotransformation by or relaxation of aortaEuropean Journal of Pharmacology, 1992