Correlation between the dexamethasone suppression test in depressed patients and clinical response
- 1 February 1984
- journal article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 141 (2) , 247-249
- https://doi.org/10.1176/ajp.141.2.247
Abstract
Eighteen psychiatric inpatients who fulfilled DSM-III criteria for major depression and who had a positive dexamethasone suppression test after admission were later retested. Of the 13 patients who exhibited cortisol suppression at discharge, two relapsed within 6 months; five remained nonsuppressors at discharge, and all either required further inpatient care or were symptomatic within 2 weeks to 4 months. Continued cortisol nonsuppression was thus associated with poor clinical response or high risk of relapse.Keywords
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